| Real-time | ✅ | | | | | |
| Identified | ✅ | ✅ | | | ✅ | ✅ |
| De-identified | | | ✅ | ✅ | ✅ | ✅ |
| Multi-source | | | | ✅ | ✅ | ✅ |
| Federated | | | ✅ | ✅ | ✅ | ✅ |
| Harmonized | | | ✅ | ✅ | ✅ | ✅ |
| Common Data Model | -- | -- | Epic Proprietary | Nference CDM | OMOP | OMOP |
| Research ready | | | ✅ | ✅ | ✅ | ✅ |
| ML Models | | | | ✅ | ✅ | ✅ |
| Ontology | | | | | ✅ | ✅ |
| Data model | | | | | ✅ | ✅ |
| Tooling | | | | | ✅ | ✅ |
| Compute platform | | | | | ✅ | ✅ |
| Data egress | | | | | ✅ | ✅ |
| Community review | | | ✅ | ✅ | ✅ | ✅ |
| Initial methods research conducted | | | | ✅ | ✅ | ✅ |
| Initial methods research with peer-review publication | | | | ✅ | ✅ | ✅ |
| Ongoing methods research conducted | | | | | ✅ | ✅ |
| Ongoing methods research with peer-review publication | | | | | ✅ | ✅ |
| Community accessible documentation of models | ✅ | ✅ | ✅ | | ✅ | ✅ |
| Community accessible documentation of algorithms | -- | -- | -- | | ✅ | ✅ |
| Published and peer-reviewed models | | | | | ✅ | ✅ |
| Published and peer-reviewed algorithms | | | | | ✅ | ✅ |
| Open source | | | | | | ✅ |
| International Reach | -- | -- | 2 continents | 1 continent | 1 continent | 6 continents |
| Countries Contributing Data | -- | -- | 5 | 1 | 4 | 54 |
| Publication Count | -- | -- | 65 | 16 | 20 | 735 |
| Data Source Count | -- | -- | 289 | 5 | 14 | 544 |
| Minimal documented time from idea to manuscript | -- | -- | -- | -- | -- | 7 days |
| Create Custom ML Models | -- | -- | -- | ✅ | | |
| Easy Cohort Creation | ✅ | ✅ | ✅ | ✅ | | |
| Sharable Cohorts Within Institute | | | ✅ | ✅ | ✅ | ✅ |
| Sharable Cohorts Across Institutes | -- | -- | ✅ | ✅ | ✅ | ✅ |
| Review Quality of Data Set | -- | -- | -- | | ✅ | ✅ |
| Generate Cohort/Study Reliability Assessments | | | | | ✅ | ✅ |
| Generate Cohort/Study Validity Assessments | | | | | ✅ | ✅ |
| Generate Study Protocol | | | | | | ✅ |
| Generate Readily Reproducible Study Packages | | | | | | ✅ |
| Licensing Model | -- | -- | ?? One time ?? | per use/compute | differs by contract | Open Source (Site absorbs full costs/responsibility) |
| Time to Stand Up | -- | -- | ?? 1.5 years ?? | ?? | | 1.5 years |
| Cost to Stand Up | -- | -- | ?? | ?? | | ?? |
| Cost to Maintain | -- | -- | ?? | ?? | | ?? |
| Upgrade Model | -- | -- | At vendor discretion | At vendor discretion | OHDSI + At vendor discretion | OHDSI community |